5th Cir.

AbbVie, Incorporated v. Murrill

July 6, 2026 ·24-30651 ·Panel Decision ·Don R. Willett · By James Taylor

The United States Court of Appeals for the Fifth Circuit affirmed a district court ruling upholding Louisiana Act 358 against challenges from pharmaceutical manufacturers. The court held that the state law regulating contract pharmacy distribution is not preempted by federal law and does not violate constitutional provisions.

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Background

Congress created the Section 340B Drug Pricing Program to provide discounted drugs to covered entities serving low-income patients. While the federal statute regulates pricing and eligibility, it remains silent on how drugs must be dispensed. Some manufacturers restricted covered entities from using contract pharmacies, prompting Louisiana to enact Act 358 to ensure access to discounted medications through such pharmacies. Pharmaceutical manufacturers challenged the state law, alleging federal preemption and constitutional violations.

The court’s reasoning

The court applied a presumption against preemption, noting that public health and consumer protection are traditional state police powers. The court found that the federal Section 340B Program does not occupy the field of drug distribution logistics, leaving room for state supplementation. Regarding the Takings Clause, the court determined the law imposes a negative obligation of non-interference rather than a physical taking. Under the Contracts Clause, the court found no substantial impairment because the federal pricing agreements did not address delivery logistics, and manufacturers entered the program with notice of potential state regulation. The court also rejected the vagueness challenge, finding the statute provided clear standards of conduct.

What it means going forward

The decision validates state laws that require pharmaceutical manufacturers to allow covered entities to use contract pharmacies for dispensing Section 340B drugs, ensuring continued access to discounted medications for vulnerable populations.